
From the last dose of opiates, the onset of withdrawal symptoms depends on what kind of opiates were used and how severely. Opiate addiction has become a widespread problem partially due to the fact that taking opiates like prescription painkillers can cause withdrawal symptoms, even with regular dosages. Six to twelve hours after the last dose of a short-acting opiate will start with subtle symptoms of withdrawal, commonly a craving for more drugs or the return of pain. Thirty hours after the last dose of a long-acting opiate, withdrawal symptoms will be a bit more severe. For all other forms of opiate abuse in high amounts, the peak of withdrawal symptoms start 72 hours after the last dose of opiates. Typically, detox from opiates happens in three phases and is best supported in a medically supervised detox program.
First is the acute withdrawal phase, which begins around the twelve-hour mark. The acute withdrawal symptoms can last for up to five days. Opiates are known to cause chronic constipation. Common symptoms of withdrawal during this phase include abdominal cramping and diarrhea as the intestines begin to regulate. Other symptoms can include depression, nausea, vomiting, and insomnia. Insomnia is often caused by “kicking,” a term unique to opiate withdrawal, similar to restless leg syndrome.
The second phase of opiate withdrawal can last two weeks. During this time, the “kicking” becomes more severe, along with chills, shaking, goosebumps, and dilated pupils. These symptoms are common for those struggling with opioid addiction, including individuals detoxing from heroin or fentanyl.
Lastly is the post-acute withdrawal phase, which can be short-term or long-term. Post-acute withdrawal syndrome can involve anxiety, depression, and insomnia as the brain adjusts to functioning without opiates.
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